ADHD update: New data on the risks of medication
From Harvard Health Publications
Harvard
Medications — chiefly the stimulants dextroamphetamine and methylphenidate — are the only proven treatment for attention deficit hyperactivity disorder (ADHD), with its symptoms of distractibility, impulsiveness, and hyperactivity. But the benefits of stimulants last only as long as patients continue to take them, and worries about the risks of long-term use are again in the news.
Blood pressure and heart problems.Stimulants raise blood pressure and heart rate. New data are fueling a debate about how dangerous this is for people who take the drugs for extended periods. In 2005 Health Canada, the Canadian equivalent of the FDA, removed Adderall XR (an extended-release form of dextroamphetamine) from the market, citing a suspicious pattern of 20 sudden deaths and 12 strokes in children and adults taking the drug. The ban was lifted when many of these patients proved to have structural heart defects.
This spring an FDA panel reported on a study of physicians’ reports on ADHD medications recorded in its Adverse Events Reporting System database. More than 300 people taking the medications died suddenly. Only 25 of these deaths appeared to be drug-related, and autopsies indicated pre-existing heart abnormalities in some of these cases. There were also 26 incidents of apparently drug-related symptoms such as chest pain, heart attacks, strokes, and arrhythmias. In a close vote, the panel members recommended the strongest possible action short of banning the drugs, a so-called black box warning of cardiovascular risk on prescription labels. They also unanimously recommended improved information sheets for physicians, patients, and families.
Comments
Pill-Poppers, the New-Age Addiction?
I know all about Pill Pushers... I served The Shrew well all those years giving her all sorts of pills from all sorts of orange bottles with white lables, as per her command. To this day, I till wonder, "WHO kept giving her PILLS for her problems?!?" My guess? She had a doctor "helping" her.
It never once occurred to me, "try one". I was too busy being The Good Daughter to ever take what was not mine.
Before the kids enter the picture of Home Sweet Home, please ask yourself: What do YOU have hiding in your medicine cabinets?
More Teens Abusing Prescription Drugs
But marijuana use is down substantially, White House report finds
By Alan Mozes, HealthDay Reporter
THURSDAY, Feb. 15 (HealthDay News) -- American teens are cutting back on their use of marijuana, but their abuse of prescription drugs in recent years has stayed the same or increased.
That's the conclusion of a report released Wednesday by White House drug czar John Walters.
From 2002 to 2005, rates of marijuana use declined from 30.1 percent to 25.8 percent. Over that same period, the use of the prescription painkiller OxyContin increased from 2.7 percent to 3.5 percent, and the use of Vicodin, another painkiller, increased from 6 percent to 6.3 percent, the Associated Press reported.
Teens are also abusing anti-anxiety drugs like Xanax and stimulants like Adderall, Walters said. Overall, 2.1 million American teens abused prescription drugs in 2005.
Teens are abusing prescription drugs, because they believe they're safer than street drugs, and they're also easier to obtain, according to Walters. He said many teens get prescription drugs over the Internet, from friends, or steal them from household medicine cabinets, the AP reported.
"The drug dealer is us," Walters said, adding that adults need to keep track of prescription drugs and dispose of them properly when the drugs expire.
The report is based on the 2005 National Survey on Drug Use and Health, a survey of 68,308 families, and the 2005 Monitoring the Future Survey of 50,000 eighth-, 10th- and 12th-graders conducted by the University of Michigan.
The findings mirror two studies released last week. The first found that, despite media reports of addicts getting prescription painkillers such as OxyContin from the Internet, most of them are actually getting these drugs from family, friends or dealers.
The second study, which looked at the abuse of these drugs in the general population, found that more teenagers are getting their hands on these powerful medications.
Dr. H. Westley Clark is director of the U.S. Center for Substance Abuse Treatment, part of the Substance Abuse and Mental Health Services Administration (SAMHSA). He said, "About 60 percent are getting their drugs from friends and family for free, while another 15 percent go and buy them from friends."
Clark was referring to numbers from SAMHSA's 2005 national survey of drug use, which also confirmed that opioid analgesic use is on the rise among teens. "So, in the case of a general population, drug dealers aren't the biggest problem either, although it's certainly no surprise that hard-core addicts are getting it that way," he said.
"Of course, we can anticipate the possibility of a growing Internet problem, particularly among young people, and we need to have some controls," Clark added. "Things change, so you can't lose vigilance. But we also do not want to exaggerate the magnitude of the current situation, and we certainly do not want to deny people with real health problems their medications."
More information
Substance Abuse and Mental Health Services Administration.
content by: www.healthday.com
Seeking straight A's, parents push for pills
Pediatricians report increasing requests for 'academic doping'
By Victoria Clayton
MSNBC contributor
Updated: 11:16 a.m. ET Sept 7, 2006
A 15-year-old girl and her parents recently came in for a chat with Dr. James Perrin, a Boston pediatrician, because they were concerned about the girl's grades. Previously an A student, she was slipping to B's, and the family was convinced attention deficit hyperactivity disorder was at fault — and that a prescription for Ritalin would boost her brainpower.
After examining the girl, Perrin determined she didn't have ADHD. The parents, who had come in demanding a prescription, left empty-handed.
Perrin, a professor of pediatrics at Harvard Medical School and spokesperson for the American Academy of Pediatrics, and other physicians say this is an increasingly common scenario in doctors' offices around the country, though there are no hard statistics on it.
Parents want their kids to excel in school, and they've heard about the illegal use of stimulants such as Ritalin and Adderall for "academic doping." Hoping to obtain the drugs legally, they pressure pediatricians for them. Some even request the drugs after openly admitting they don't believe their child has ADHD.
“I spoke with [some] colleagues the other day and they mentioned three cases recently where parents blatantly asked for the medication so that their children would perform better in school, yet there were no other indications that the child had ADHD,” says Dr. Nick Yates, a pediatrician and director of medical ethics for Mercy Hospital in Buffalo, N.Y.
“I’m very concerned that there’s a fair amount — and we don’t know how much — [of ADHD drugs] being prescribed and used for off-label purposes," says Yates.
Academic doping — using these stimulant prescriptions in an effort to enhance focus, concentration and mental stamina — first started on college campuses, especially Ivy League and exclusive, competitive schools. Now, the problem is filtering down to secondary schools, Yates says, and more parents are playing a role in obtaining prescription ADHD medication for their teenagers.
Yates isn't entirely surprised that parents ask for it. He believes that most families simply have a heartfelt — if shockingly misdirected — desire for their children to do their best.
Parents can be overly eager to blame poor grades on a medical condition rather than looking for other explanations, says Dr. Michael Rater, medical director of the Adolescent and Residential Treatment Program at McLean Hospital in Belmont, Mass. “It’s usually that parents are just trying to understand their children’s struggles in a narrative that makes sense to them,” he says.
Yet some parents will do whatever it takes to keep opportunities from slipping through a child's fingers — even outright lying to doctors to get the drugs, says Rater.
And some pill-eager parents aren't just seeking to level the playing field, they're trying to make their kids superstars, says Dr. Martin Stein, a professor of clinical pediatrics at University of California, San Diego.
“I see patients who come from privileged backgrounds and lower-level economic backgrounds and there’s a tremendous difference in parental expectations,” Stein says.
Privileged kids tend to have parents who will push them to be the academic cream of the crop and when they aren’t, they’ll start looking for reasons why, he says. “I tell them that honor roll, a merit scholarship or acceptance in an Ivy League school is not the end point. That would be poor medicine.”
Safety issues
The concerns with academic doping aren't just ethical.
"The medications in general have a long safety record for people who need them but when you use a drug for off-label purposes, there are additional safety concerns,” says Yates.
Although doctors generally agree that side effects from the medications are minimal for most kids, there is an extensive, and sometimes frightening, list of possibilities.
Commonly reported side effects include difficulty sleeping, loss of appetite, irritability, stomachaches, headaches, blurry vision, nausea, dizziness, drowsiness and tics and tremors. There have been concerns that ADHD medication temporarily delays growth, and one study found that up to 5 percent of children experience tactile hallucinations, often involving a sensation that bugs or snakes are crawling on their bodies. The FDA recently announced that certain ADHD drugs should caution users about the risks of serious heart problems and psychotic behavior.
A 2004 rat study conducted by the National Institutes of Health and McLean Hospital/Harvard Medical School suggested that children who take prescription drugs for ADHD but do not have the disorder may be at higher risk for developing depressive symptoms in adulthood. The study was particularly looking at the issue of misdiagnosis but it raises obvious concerns for the future of young people who are electing to take the medicine for no other reason than to do well in school.
In addition, Yates says that possible dependency issues, either psychological or physical, could occur when the drugs are being misused. It’s widely acknowledged that some kids abuse the drugs to get high. The pills are often crushed and snorted or even injected.
Searching out other explanations
While ADHD drugs aren't a quick fix for a lackluster report card, Stein says that poor academic performance is cause for investigation — sometimes for ADHD but also for a host of other problems. “If it was brought to my attention that someone’s grades were going down even to B's I would start looking at the whole picture," he says.
Stein says there are a variety of learning disabilities and myriad situations that are not medical but still may have an impact on a child’s academic performance.
“It could also be something situational like a divorce or a relationship with another person this kid is having," he says. "It could be that a parent has lost a job and there’s financial stress in the family.”
Depression, anxiety and other mental disorders might also be at work.
“ADHD is only one of the possibilities, and I make a point to put that at the end,” says Stein.
Perrin says he’s particularly skeptical when he’s treated a patient for many years and attention problems are only brought up once the child reaches high school. The 15-year-old girl in question, for example, had been his patient for more than a decade. He concluded that she was just a normal teen experiencing the distractions — sports, boys, friends — that teens experience.
He said that even if he had ultimately determined that the girl had ADHD, medication would not have been a speedy remedy. “True ADHD is not something that is dealt with quickly,” he says.
Scrupulous doctors, Perrin says, will take numerous office visits and much investigation before diagnosing the problem. And, if ADHD is diagnosed, they will not just prescribe medication. They’ll also prescribe behavioral therapy (sometimes for the entire family) and recommend fairly significant changes in the child’s home and learning environment.
Furthermore, doctors warn that if a kid doesn’t have ADHD, the benefit from taking the drugs is unpredictable and, despite the lore, most likely extremely modest. Parents of unmotivated kids may be particularly disappointed.
“One of the biggest problems in adolescent mental health is motivation,” says Rater. “And this medication doesn’t effect motivation. If a kid is not all that motivated, it’s really not going to help.”
Victoria Clayton is a freelance writer based in California and co-author of "Fearless Pregnancy: Wisdom and Reassurance from a Doctor, a Midwife and a Mom," published by Fair Winds Press.
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I don't know how smart parents are, but kids are much smarter.
Double-dosing medication can be read here: http://www.msnbc.msn.com/id/20842489/wid/11915773?gt1=10412
See also my post, Ritalin and Desperate Housewives. (Not bad for a self-taught chick, huh?)
Safe alternative: time and patience
Treating ADHD Without Medication
By Dr. Rob for MSN Health & Fitness
http://health.msn.com/health-topics/adhd/articlepage.aspx?cp-documentid=100145250
Q: My 9-year-old grandson has ADHD and his parents don't want to put him on medication. How can we help him?
A: Probably the best way to help your grandchild is to support his parents in their decision. I know it’s hard to sit back and watch, but by following one of the non-medical treatment plans I will discuss, you will have the opportunity to play a large part in helping both your grandson and his parents.
The treatment of attention-deficit/hyperactivity disorder (or ADHD) in children usually involves a combination of medication, education and behavioral intervention; however, it is not unusual for parents to want drug-free options. One proven method is behavioral therapy, or what is also referred to as “psychosocial treatment.” This approach requires an experienced therapist or educator to teach specific techniques geared toward the child and their parents, as well as the child’s teachers and extended family. While these methods are aimed at improving the child’s behaviors, they have also been known to improve the child’s symptoms and, therefore, some of the resulting problems. Unlike medication, this method takes more time, needs to have goals where achievements are measured in small steps, requires consistency throughout the day in whatever environment the child happens to be (school, home, friend’s house, others) and needs to be in force for the “long haul,” and not for just a few weeks. As you can tell, it is a method that requires the dedication of parents, extended family, teachers and the affected child.
When gearing up for this approach, it is important to identify which specific type of ADHD affects your grandson. For example, does he have the predominantly inattentive type? If so, he may be prone to many of the following symptoms:
If your grandson has the predominantly hyperactive/impulsive type, many of these behaviors will be evident:
If he seems to have many characteristics from both of the above categories, he would then be diagnosed with ADHD, combined type.
In looking at the above symptoms, many parents may say, “My child does that.” However, in considering the diagnosis of ADHD, we are taking into consideration the following:
Once the specific symptoms affecting the child are identified, behavioral treatment is designed to teach new skills to all those involved with handling the results of those problems. For example, if the child keeps forgetting to brush her teeth, the behavioral treatment would be aimed at establishing a routine to help her accomplish this task. If the child acts like a bully to other children, approaches for more effective interactions are designed to help him learn to be friends with his peers. Other techniques used to help the parents assist their child include, but are not limited to:
Behavioral therapy works best when it is also utilized at school and during times of interaction with other children. This makes it vitally important for parents to work closely with their child, child’s teacher, mental health professional and local ADHD support group.
Untreated or under-treated ADHD can lead to wide-ranging problems beyond the symptoms of inattentiveness or hyperactivity and impulsivity. Some of these life-affecting problems include failure at school, depression, increased anxiety and social isolation. In my opinion, this is a strong reason to include behavioral therapy as part of any plan that attempts to treat ADHD.
For more information on attention deficit/hyperactivity disorder, please visit CHADD -Children and Adults with Attention Deficit Disorders, a national non-profit organization representing children and adults with ADHD.
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